General Information


Quadris Xtra is a broad spectrum, preventative fungicide with systemic and curative properties recommended for the control of many important plant diseases. Quadris Xtra may be applied as a foliar spray in alternating spray programs or in tank mixes with other crop protection products. All applications should be made according to the use directions that follow.


Do not use in nurseries, greenhouses or landscape plantings.

Under certain conditions conducive to extended infection periods, use another registered fungicide for additional applications if the maximum amount of product has been applied.

The active ingredient(s) in this product may have effects on federally listed threatened and endangered species or critical habitat in some counties. When using this product, you must follow the measures contained in the County Bulletin for the county in which you are applying the pesticide. To determine whether your County has a Bulletin consult Bulletins also may be available from local pesticide dealers, extension offices, or State pesticide agencies.


Quadris Xtra demonstrates some phytotoxic effects when mixed with products that are formulated as ECs. These effects are enhanced if applications are made under cool, cloudy conditions and these conditions remain for several days following application. In addition, adjuvants that contain some form of silicone can contribute to phytotoxicity. Under certain environmental conditions, tank mixes of Quadris Xtra plus herbicides and/or fertilizers may cause crop injury.


Quadris Xtra is extremely phytotoxic to certain apple varieties.

AVOID SPRAY DRIFT. Extreme care must be used to prevent injury to apple trees (and apple fruit).

DO NOT spray Quadris Xtra where spray drift may reach apple trees.

DO NOT spray when conditions favor drift beyond area intended for application. Conditions which may contribute to drift include thermal inversion, wind speed and direction, sprayer nozzle/pressure combinations, spray droplet size, etc. Contact your State extension agent for spray drift prevention guidelines in your area.

DO NOT use spray equipment which has been previously used to apply Quadris Xtra to spray apple trees. Even trace amounts can cause unacceptable phytotoxicity to certain apple and crabapple varieties.



Quadris Xtra should be integrated into an overall disease and pest management strategy whenever the use of a fungicide is required. Cultural practices known to reduce disease development should be followed. The SPECIFIC USE DIRECTIONS section in the label identifies specific IPM recommendations for each crop. Consult your local agricultural authorities for additional IPM strategies established for your area. Quadris Xtra may be used in State Agricultural Extension advisory (disease forecasting) programs which recommend application timing based on environmental factors favorable for disease development.


Quadris Xtra is a mixture of Group 3 (cyproconazole) and Group 11 (azoxystrobin) fungicides. Quadris Xtra has two modes of action: (1) DMI (demethylation inhibitor of sterol biosynthesis) [Group 3], and (2) inhibitor of the Qo (quinone outside) site within the electron transport system (QoI) [Group 11]. Fungal pathogens can develop resistance to products with the same mode of action when used repeatedly. Because resistance development cannot be predicted, use of this product should conform to resistance management strategies established for the crop and use area. Consult your local or State agricultural authorities for resistance management strategies that are complementary to those in the label. Resistance management strategies may include rotating and/or tank mixing with products having different modes of action or limiting the total number of applications per season. Syngenta encourages responsible resistance management to ensure effective long-term control of the fungal diseases on the label.

Follow specific crop recommendations that limit the total number of sprays on a crop and the required alternations with fungicides from other resistance management groups. In situations requiring multiple sprays (more than two), develop season long spray programs for Group 11 (QoI) fungicides. The program should meet the goal of no more than 1/3 of the total sprays per season, when a Group 11 fungicide is used as a solo product, or 1/2 the total sprays when a Group 11 fungicide is used in a mixture. Programs that include both solo Group 11 products and/or mixes containing Group 11 products should be no more than 1/2 the total sprays.

Quadris Xtra should not be alternated or tank mixed with any fungicide to which resistance has already developed.


Apply Quadris Xtra at rates and timings as described in the label. Quadris Xtra may be applied by ground, by air, or via chemigation. Refer to crop section for specific directions.

Quadris Xtra should be applied with a minimum of 10 GPA via ground application equipment and 2 GPA via aerial application equipment.

Limitations, Restrictions, and Exceptions


Application Directions: Coverage and penetration are important for best results. Use sufficient water volume to provide thorough and uniform plant coverage. Applications may be made by ground, air or chemigation. Addition of an additive with spreading and penetrating qualities will enhance coverage and efficacy.

Resistance Management: No more than two foliar applications of Quadris Xtra or other strobilurin fungicides should be made per growing season. Do not alternate or tank mix with fungicides to which resistance has developed in the pathogen population.


For diseases other than soybean rust: For best results, begin Quadris Xtra applications prior to disease development. Use the higher rates under conditions favorable for severe disease pressure, dense plant canopies, or when disease is present. Contact extension personnel for local economic thresholds and timings for specific diseases in your area. An adjuvant may be added at recommended rates to improve coverage.

Specific Use Restrictions:

(1) Do not apply more than 13.6 fl.oz. Quadris Xtra/A/season.

(2) Do not apply within 30 days of harvest of soybeans (bean).

(3) Do not graze forage within 14 days of an application.

(4) Do not apply more than 0.072 lb. a.i./A/year of cyproconazole containing products.

(5) Do not apply more than 1.5 lb. a.i./A/year of azoxystrobin containing products.

(6) Do not use soybean forage or hay as livestock feed if making more than one application at 6.8 fl. oz. product/A.

Pre-Harvest Interval

30 days

Restricted Entry Interval

12 hours