General Information


Quadris is extremely phytotoxic to certain apple varieties.
AVOID SPRAY DRIFT. Extreme care must be used to prevent injury to apple trees (and apple fruit).
DO NOT spray Quadris where spray drift may reach apple trees.
DO NOT spray when conditions favor drift beyond area intended for application.
Conditions which may contribute to drift include thermal inversion, wind speed and direction, sprayer nozzle/pressure combinations, spray droplet size, etc. Contact your State extension agent for spray drift prevention guidelines in your area.
DO NOT use spray equipment which has been previously used to apply Quadris to spray apple trees. Even trace amounts can cause unacceptable phytotoxicity to certain apple and crabapple varieties.

Quadris is a broad spectrum, preventative fungicide with systemic and curative properties recommended for the control of many important plant diseases. Quadris Flowable Fungicide is a member of Syngenta’s Plant Performance product line and may also improve the yield and/or quality of the crop. These additional benefits are due to positive effects on plant physiology. The effects may vary according to factors such as the crop, crop hybrid, or environment. Quadris may be applied as a foliar spray in alternating spray programs or in tank mixes with other registered crop protection products. All applications must be made according to the use directions that follow.
Restrictions for Resistance Management Purposes
Greenhouse Use: To help manage fungicide resistance, do not use for commercial transplant production in the greenhouse except where specified on the label.

Application: Thorough coverage is necessary to provide good disease control. Make no more spray solution than is needed for application. Avoid spray overlap, as crop injury may occur.

Adjuvants: When an adjuvant is to be used with this product, the use of an adjuvant that meets the standards of the Chemical Producers and Distributors Association (CPDA) adjuvant certification is recommended.
Efficacy: Under certain conditions conducive to extended infection periods, use another registered fungicide for additional applications if maximum amount of Quadris has been used. If resistant isolates to Group 11 fungicides are present, efficacy can be reduced for certain diseases. The higher rates in the rate range and/or shorter spray intervals may be required under conditions of heavy infection pressure, with highly susceptible varieties, or when environmental conditions are conducive to disease.


Quadris should be integrated into an overall disease and pest management strategy whenever the use of a fungicide is required. Cultural practices known to reduce disease development should be followed. This should include selection of varieties with disease tolerance, removal of plant debris in which inoculum overwinters, and proper timing and placement of irrigation. Consult your local agricultural authorities for additional IPM strategies established for your area. Quadris may be used in State Agricultural Extension advisory (disease forecasting) programs which recommend application timing based on environmental factors favorable for disease development.

Crop Tolerance: Plant tolerance has been found to be acceptable for all crops on the label, however, not all possible tank-mix combinations have been tested under all conditions.

When possible, it is recommended to test the combinations on a small portion of the crop to ensure that a phytotoxic response will not occur as a result of application. See Product Use Precautions for apple phytotoxicity information.


Quadris (azoxystrobin) is a Group 11 fungicide. The mode of action for Quadris is the inhibition of the Qol (quinone outside) site within the electron transport system [Group 11]. Fungal pathogens can develop resistance to products with the same mode of action when used repeatedly. Because resistance development cannot be predicted, use of this product should conform to resistance management strategies established for the crop and use area. Consult your local or State agricultural authorities for resistance management strategies that are complementary to those in this label. Resistance management strategies may include alternating and/or tank-mixing with products having different modes of action or limiting the total number of applications per season. Syngenta encourages responsible resistance management to ensure effective long-term control of the fungal diseases on this label.

Follow the crop specific resistance management recommendations in the directions for use.

In situations requiring multiple sprays, develop season long spray programs for Group 11 (QoI) fungicides. In crops where two sequential Group 11 fungicide applications are made, they should be alternated with two or more applications of a fungicide that is not in Group 11. If more than 12 applications are made, observe the following guidelines:

- When using a QoI fungicide as a solo product, the number of applications must be no more than 1/3 (33%) of the total number of fungicide applications per season.
- For QoI mixes in programs in which tank mixes or premixes of QoI with mixing partners of a different mode of action are utilized, the number of QoI containing applications must be no more than 1/2 (50%) of the total number of fungicide applications per season.

- In programs in which applications of QoI are made with both solo products and mixtures, the number of QoI containing applications must be no more than ½ (50%) of the total number of fungicide applications per season.

If a Group 11 fungicide is applied to the seed or soil, do not make another application with a Group 11 fungicide for at least 3 weeks.


For those crops that have specific use directions for soilborne disease control:
Quadris can provide control of many soilborne diseases if applied early in the growing season. Specific applications for soilborne diseases include in-furrow applications and banded applications applied over the row, either shortly after plant emergence or during herbicide applications or cultivation. These applications will provide control of pre or postemergence damping off and diseases that infect plants at the soil-plant interface.
The use of either type of application depends on the cultural practices in the region.
In some locations, one type of application may provide better disease control than the other, depending on the timing of the disease epidemic. Seedling diseases are generally controlled by in-furrow applications while banded applications are more effective against soilborne diseases that develop later in the season. Consult your local expert to get some guidance regarding application type.
Under cool, wet conditions, crop injury from soil directed applications can occur.


- Apply Quadris prior to infection as a directed spray to the soil, using single or multiple nozzles, adjusted to provide thorough coverage of the lower stems and the soil surface surrounding the plants.
- Band width should be limited to 7 inches or less.
- Apply Quadris at a rate of 0.40-0.80 fl oz product (0.10-0.20 oz ai)/1000 row feet.
For banded applications on 22-inch rows, the maximum application rate is 0.70 fl oz/1000 row feet.

- These applications come into contact with the foliage and are counted as foliar applications when considering resistance management.
- They may be applied during cultivation or hilling operations to provide soil incorporation.

- Apply Quadris as an in-furrow spray in 3-15 gallons of water at planting.
- Mount the spray nozzle so the spray is directed into the furrow just before the seeds are covered.
- Use the higher rate when the weather conditions are expected to be conducive for disease development, if the field has a history of Pythium problems, or if minimum/low till programs are in place.

Limitations, Restrictions, and Exceptions


Apply prior to disease development.

An adjuvant may be added at recommended rates.

Application Directions: Quadris can be applied by either ground, chemigation, or aerial application.

Specific Use Restrictions:

- Do not apply within 7 days (7-day PHI) for forage and hay.

- Do not apply within 14 days of grazing (14-day PHI).

- Do not apply within 30 days of harvest (30-day PHI).

Pre-Harvest Interval

30 days

Restricted Entry Interval

4 hours

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